{"name":"AlignmentViewer","description":"AlignmentViewer is multiple sequence alignment viewer for protein families with flexible visualization, analysis tools and links to protein family databases. It can handle protein families with tens of thousand of sequences and is particularly suitable for evolutionary coupling analysis, preparing the computation of protein 3D structures and detection of functionally constrained interactions.","homepage":"http://alignmentviewer.org","biotoolsID":"alignmentviewer","biotoolsCURIE":"biotools:alignmentviewer","version":[],"otherID":[],"relation":[],"function":[{"operation":[{"uri":"http://edamontology.org/operation_0492","term":"Multiple sequence alignment"},{"uri":"http://edamontology.org/operation_0564","term":"Sequence visualisation"},{"uri":"http://edamontology.org/operation_2479","term":"Protein sequence analysis"}],"input":[],"output":[],"note":null,"cmd":null}],"toolType":[],"topic":[{"uri":"http://edamontology.org/topic_0623","term":"Gene and protein families"},{"uri":"http://edamontology.org/topic_0080","term":"Sequence analysis"},{"uri":"http://edamontology.org/topic_3168","term":"Sequencing"},{"uri":"http://edamontology.org/topic_0160","term":"Sequence sites, features and motifs"},{"uri":"http://edamontology.org/topic_0084","term":"Phylogeny"}],"operatingSystem":[],"language":["JavaScript"],"license":"MIT","collectionID":[],"maturity":null,"cost":null,"accessibility":null,"elixirPlatform":[],"elixirNode":[],"elixirCommunity":[],"link":[{"url":"https://github.com/sanderlab/alignmentviewer","type":["Repository"],"note":null}],"download":[],"documentation":[],"publication":[{"doi":"10.12688/F1000RESEARCH.22242.2","pmid":"33123346","pmcid":"PMC7570326","type":[],"version":null,"note":null,"metadata":{"title":"AlignmentViewer: Sequence Analysis of Large Protein Families","abstract":"© 2020 Reguant R et al.AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org.","date":"2020-01-01T00:00:00Z","citationCount":0,"authors":[{"name":"Sander C."},{"name":"Gauthier N.P."},{"name":"Reguant R."},{"name":"Antipin Y."},{"name":"Sheridan R."},{"name":"Dallago C."},{"name":"Diamantoukos D."},{"name":"Luna A."}],"journal":"F1000Research"}}],"credit":[{"name":"Chris Sander","email":"sander.research@gmail.com","url":null,"orcidid":"https://orcid.org/0000-0001-6059-6270","gridid":null,"rorid":null,"fundrefid":null,"typeEntity":"Person","typeRole":[],"note":null},{"name":"Nicholas Paul Gauthier","email":"nicholasp_gauthier@dfci.harvard.edu","url":null,"orcidid":null,"gridid":null,"rorid":null,"fundrefid":null,"typeEntity":"Person","typeRole":[],"note":null}],"owner":"Kigaard","additionDate":"2021-01-18T11:29:11Z","lastUpdate":"2021-01-23T13:57:34Z","editPermission":{"type":"private","authors":[]},"validated":1,"homepage_status":0,"elixir_badge":0,"confidence_flag":"tool"}