JASPARJASPAR is a high-quality, open-access database that provides manually curated, non-redundant transcription factor (TF) binding profiles for six taxonomic groups (fungi, insecta, nematoda, plantae, urochordata, vertebrata). These profiles are stored as position frequency matrices (PFMs), which can be transformed into models to predict TF binding sites (TFBS) in DNA sequences. The database collects motifs both internally, analyzing sequences using a custom motif discovery pipeline, and externally from publications and other resources. All selected motifs are manually curated for quality and supporting evidence. JASPAR now offers a tool for TFBS enrichment analysis in user-provided genomic regions. Data is accessible through the JASPAR website, its RESTful API, Bioconductor, or the Python package pyJASPAR.http://jaspar.genereg.net/jasparbiotools:jasparRRID:SCR_003030rridDatabase portalWeb applicationhttp://edamontology.org/topic_3071Biological databaseshttp://edamontology.org/topic_0749Transcription factors and regulatory siteshttp://edamontology.org/topic_0204Gene regulationhttp://edamontology.org/topic_0622Genomicshttp://edamontology.org/topic_2815Human biologyhttp://edamontology.org/topic_0780Plant biologyhttp://edamontology.org/topic_0621Model organismsLinuxWindowsMacPythonCC-BY-4.0ELIXIR-NOELIXIR-NorwayJASPARMatureFree of chargeOpen accessFederated Human DataPlant SciencesNorwayhttp://edamontology.org/operation_2421Database searchhttp://edamontology.org/data_2755Transcription factor namehttp://edamontology.org/data_1077Transcription factor identifierhttp://edamontology.org/data_1868Taxonhttp://edamontology.org/data_2732Family namehttp://edamontology.org/data_1045Species namehttp://edamontology.org/data_2291UniProt IDhttp://edamontology.org/data_3671Text

http://edamontology.org/data_1119JASPAR profile IDhttp://edamontology.org/format_1367JASPAR formathttp://edamontology.org/format_3464JSONhttp://edamontology.org/format_2330Textual formathttp://edamontology.org/format_3752CSVhttp://edamontology.org/format_3475TSVhttp://edamontology.org/format_3750YAML

http://edamontology.org/operation_0445Transcription factor binding site predictionhttp://edamontology.org/data_3494DNA sequencehttp://edamontology.org/format_1929FASTAhttp://edamontology.org/data_1119JASPAR profile ID

http://edamontology.org/data_1119JASPAR profile ID

https://groups.google.com/g/jasparDiscussion forumhttps://bitbucket.org/CBGR/jaspar/src/master/Repositoryhttps://elixir.no/helpdeskHelpdeskHelpdesk and support for ELIXIR Norway serviceshttps://doi.org/10.5281/zenodo.6860527Repositoryhttps://doi.org/10.5281/zenodo.6860555Repositoryhttps://bioconductor.org/packages/release/data/annotation/html/JASPAR2022.htmlSoftware cataloguehttps://pypi.org/project/pyjaspar/Software cataloguehttps://twitter.com/jaspar_dbSocial mediahttp://jaspar.genereg.net/downloads/Downloads pagehttps://jaspar.genereg.net/api/API specificationhttps://github.com/asntech/pyjasparSource codeRepository for pyJASPARhttp://jaspar.genereg.net/docs/GeneralGovernancehttp://jaspar.genereg.net/faq/FAQhttp://jaspar.genereg.net/api/v1/docs/API documentationhttps://pyjaspar.readthedocs.io/en/latest/Citation instructionsCommand-line optionsInstallation instructionsUser manualDocumentation for pyJASPARhttps://bioconductor.org/packages/release/data/annotation/vignettes/JASPAR2022/inst/doc/JASPAR2022.htmlCommand-line optionsUser manualDocumentation for the Bioconductor packagejaspar_apiusedBytfbstoolsusedBytfmotifviewusedByjaspextractusedByaimodulesusedBybioconductorusesbiocfilecacheusesbiopythonuses10.1093/nar/gkab111334850907PMC8728201Primary910.1093/nar/gkz100131701148PMC7145627Primary810.1093/nar/gkx112629140473PMC5753243Primary201810.1093/bioinformatics/btx80429253085Usage10.1093/nar/gkv117626531826Primary201610.1093/nar/gkt99724194598Primary5.0_ALPHA10.1093/nar/gkp95019906716Primary410.1093/nar/gkm95518006571Primary310.1093/nar/gkj11516381983Primary210.1093/nar/gkh01214681366Primary1Albin Sandelinalbin@binf.ku.dkhttps://albinsandelin.wixsite.com/sandelinlabhttp://orcid.org/0000-0002-7109-7378PersonPrimary contactBoris Lenhardb.lenhard@imperial.ac.ukhttps://lms.mrc.ac.uk/research-group/computational-regulatory-genomics/http://orcid.org/0000-0002-1114-1509PersonPrimary contactWyeth Wassermanwyeth@cmmt.ubc.cahttps://cmmt.ubc.ca/wasserman-lab/http://orcid.org/0000-0001-6098-6412PersonPrimary contactFrançois Parcyfrancois.parcy@cea.frhttps://www.lpcv.fr/en/Pages/Flo_Re/Presentation.aspxhttps://orcid.org/0000-0003-2191-500XPersonPrimary contactAnthony Mathelieranthony.mathelier@ncmm.uio.nohttps://mathelierlab.com/http://orcid.org/0000-0001-5127-5459PersonPrimary contactThe Norwegian Bioinformatics Platform (ELIXIR-Norway) Helpdesksupport@elixir.nohttps://elixir.no/helpdeskConsortiumSupportHelpdesk and support for ELIXIR Norway servicesAlejandro AguirrePersonContributorBenoit Ballesterhttps://orcid.org/0000-0002-0834-7135PersonContributorDamir Baranasichttps://orcid.org/0000-0001-5948-0932PersonContributorRomain Blanc-Mathieuhttps://orcid.org/0000-0002-9485-6330PersonContributorPaul BoddiePersonContributorMaintainerSupportJaime A Castro-Mondragonhttps://orcid.org/0000-0003-4069-357XPersonContributorOriol Forneshttps://orcid.org/0000-0002-5969-3054PersonContributorFayrouz Hammalhttps://orcid.org/0000-0002-7612-4953PersonContributorAziz Khanhttps://orcid.org/0000-0002-6459-6224PersonContributorMaintainerSupportRoza Berhanu Lemmahttps://orcid.org/0000-0003-1069-8011PersonContributorTiffany Y LeungPersonContributorJérémy Lucashttps://orcid.org/0000-0002-2252-4732PersonContributorNicolás Manosalva Pérezhttps://orcid.org/0000-0002-1559-7802PersonContributorIeva Rauluseviciutehttps://orcid.org/0000-0001-9253-8825PersonContributorRafael Riudavets-Puighttps://orcid.org/0000-0002-2855-9952PersonContributorDaniel Schmelterhttps://orcid.org/0000-0002-7311-0599PersonContributorLaura Turchihttps://orcid.org/0000-0002-2791-5505PersonContributorKlaas Vandepoelehttps://orcid.org/0000-0003-4790-2725PersonContributorThe Research Council of Norwayhttp://www.forskningsradet.no/en/Home_page/1177315753906grid.13985.3600epmv14910.13039/501100005416Funding agencyErin Calhounerin.calhoun@uit.nohttps://orcid.org/0009-0003-3752-7156PersonDocumentorCuration for bio.tools profile - please contact me with updates/corrections