PPI-AffinityA Web Tool for the Prediction and Optimization of Protein-Peptide and Protein-Protein Binding Affinity.https://protdcal.zmb.uni-due.de/PPIAffinityppi-affinitybiotools:ppi-affinityWeb applicationhttp://edamontology.org/topic_0154Small moleculeshttp://edamontology.org/topic_0128Protein interactionshttp://edamontology.org/topic_0121Proteomicshttp://edamontology.org/topic_0199Genetic variationhttp://edamontology.org/topic_3474Machine learningMacLinuxWindowsFree of chargeOpen accesshttp://edamontology.org/operation_3938Virtual screeninghttp://edamontology.org/operation_2492Protein interaction predictionhttp://edamontology.org/operation_0337Visualisationhttp://edamontology.org/operation_2464Protein-protein binding site prediction10.1021/acs.jproteome.2c0002035654412PMC9361347Elsa Sanchez-Garciahttps://orcid.org/0000-0002-9211-5803Michael Ehrmannhttps://orcid.org/0000-0002-1927-260XJan Münchhttps://orcid.org/0000-0001-7316-7141Sandra Romero-Molina