{"name":"SelSim","description":"A program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection.","homepage":"https://popmodels.cancercontrol.cancer.gov/gsr/packages/selsim","biotoolsID":"selsim","biotoolsCURIE":"biotools:selsim","version":[],"otherID":[],"relation":[],"function":[{"operation":[{"uri":"http://edamontology.org/operation_2426","term":"Modelling and simulation"}],"input":[],"output":[],"note":null,"cmd":null}],"toolType":["Command-line tool"],"topic":[{"uri":"http://edamontology.org/topic_3524","term":"Simulation experiment"}],"operatingSystem":[],"language":["C++"],"license":"Not licensed","collectionID":["Animal and Crop Genomics"],"maturity":null,"cost":null,"accessibility":null,"elixirPlatform":[],"elixirNode":[],"elixirCommunity":[],"link":[],"download":[],"documentation":[{"url":"https://github.com/trvrb/selsim","type":["User manual"],"note":null}],"publication":[{"doi":"10.1093/bioinformatics/bth417","pmid":"15271777","pmcid":null,"type":["Primary"],"version":null,"note":null,"metadata":{"title":"SelSim: A program to simulate population genetic data with natural selection and recombination","abstract":"Summary: SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection. © Oxford University Press 2004; all rights reserved.","date":"2004-12-12T00:00:00Z","citationCount":96,"authors":[{"name":"Spencer C.C.A."},{"name":"Coop G."}],"journal":"Bioinformatics"}}],"credit":[{"name":null,"email":"spencer@well.ox.ac.uk","url":null,"orcidid":null,"gridid":null,"rorid":null,"fundrefid":null,"typeEntity":"Person","typeRole":["Primary contact"],"note":null},{"name":null,"email":"gmcoop@ucdavis.edu","url":null,"orcidid":null,"gridid":null,"rorid":null,"fundrefid":null,"typeEntity":"Person","typeRole":["Primary contact"],"note":null}],"owner":"admin","additionDate":"2017-08-20T15:58:56Z","lastUpdate":"2024-11-25T14:02:12.532420Z","editPermission":{"type":"group","authors":["animalandcropgenomics"]},"validated":1,"homepage_status":0,"elixir_badge":0,"confidence_flag":null}