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    note: predicts the presence and location of signal peptide cleavage sites in amino
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    metadata:
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      journal: Nature Methods
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  additionDate: '2022-03-25T08:59:55.062522Z'
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  description: Neural networks prediction of whether a human gene is located at the
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    note: network ensemble
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      abstract: The mitotic spindle is an essential molecular machine involved in
        cell division, whose composition has been studied extensively by detailed
        cellular biology, high-throughput proteomics, and RNA interference experiments.
        However, because of its dynamic organization and complex regulation it is
        difficult to obtain a complete description of its molecular composition. We
        have implemented an integrated computational approach to characterize novel
        human spindle components and have analysed in detail the individual candidates
        predicted to be spindle proteins, as well as the network of predicted relations
        connecting known and putative spindle proteins. The subsequent experimental
        validation of a number of predicted novel proteins confirmed not only their
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        found that 75% of our tested proteins are localizing to the spindle apparatus
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        the still hidden regions of the human spindle system. © 2012 Rojas et al.
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  additionDate: '2017-05-12T10:55:31Z'
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      abstract: © 2016 The Author(s)Sequence databases, such as NCBI, are a very important
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        Downloader is an open source program aimed at simplifying obtaining large
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next: null
previous: null
